![]() Antidepressants are the most common medication used to treat cataplexy. Future studies should clarify the perioperative risk associated with narcolepsy to optimize the care and safety of narcoleptic patients. For people with type 1 narcolepsy, medication can help treat cataplexy, hallucinations, and sleep paralysis. Respondents frequently self-report adverse events in the perioperative period. Enhanced education of perioperative providers about potential narcolepsy-related issues is essential. Most narcoleptic patients report not receiving counseling regarding potential worsening of narcolepsy symptoms postanesthesia or an increased risk of drowsy driving. 001), and inadequate pain relief (odds ratio, 1.77 P <. 001), difficulty waking (odds ratio, 2.1 P =. Undergoing 5 or more separate surgeries or procedures was associated with a 2-fold increase in self-reported complications (odds ratio, 2.2 P =. Of the total sample, 18% indicated surgical complications. 001 and antidepressant medications: odds ratio, 6.5 P =. 03) and medication withdrawal symptoms (stimulant medications: odds ratio, 3.0 P >. Subjects with cataplexy more frequently reported surgical complications (70% vs 31% P =. More than half of respondents reported adverse events (medication withdrawal symptoms, inadequate pain relief, increased cataplexy). Most respondents did not receive counseling regarding the possibility of increased sleepiness (70%), cataplexy (90%), or drowsy driving (59%) postanesthesia. ![]() ![]() Respondents were mostly women (79.5%) and Caucasian (84.9%), with a mean age of 45 ± 16 years. Descriptive, comparative statistics and logistic regression were utilized. ![]() One thousand and twenty respondents reported a diagnosis of narcolepsy and 1 or more procedures under anesthesia or sedation. Recruitment was via the Narcolepsy Network's list-serve and a Facebook link to the survey. This study sought to determine the perioperative experience of narcoleptic patients undergoing anesthesia or sedation, the frequency of perioperative counseling, and self-reported surgical complications.Ī 22-question survey was developed by expert consensus and distributed by the Narcolepsy Network. Narcolepsy has a major impact on workableness and quality of life. See XYREM prescribing information & BOXED Warning about serious side effects, CNS depression, misuse and abuse. Patients with narcolepsy may be at increased perioperative risk due to the interactions among anesthesia, narcolepsy, and narcolepsy medications. Narcolepsy with cataplexy is most commonly caused by an immune-mediated process including genetic and environmental factors, resulting in the selective loss of hypocretin-producing neurons. XYREM (sodium oxybate)Now approved for use in adults and children ages 7 and older to help treat cataplexy and excessive daytime sleepiness (EDS) in narcolepsy. ![]()
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